NFATC4 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | NFATC4, NF-AT3, NF-ATC4, NFAT3, nuclear factor of activated T-cells 4, nuclear factor of activated T cells 4 |
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External IDs | OMIM: 602699; MGI: 1920431; HomoloGene: 3349; GeneCards: NFATC4; OMA:NFATC4 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 14 (human)[1] |
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| Band | 14q12 | Start | 24,365,673 bp[1] |
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End | 24,379,604 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 14 (mouse)[2] |
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| Band | 14|14 C3 | Start | 56,060,601 bp[2] |
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End | 56,071,400 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - canal of the cervix
- right ovary
- left ovary
- stromal cell of endometrium
- body of uterus
- left uterine tube
- myometrium
- gastric mucosa
- muscle layer of sigmoid colon
- right coronary artery
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| Top expressed in | - gastrula
- external carotid artery
- internal carotid artery
- genital tubercle
- maxillary prominence
- mandibular prominence
- ventricular zone
- hand
- calvaria
- abdominal wall
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - DNA binding
- DNA-binding transcription factor activity
- transcription coactivator activity
- transcription factor binding
- RNA polymerase II cis-regulatory region sequence-specific DNA binding
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- protein binding
- DNA-binding transcription factor activity, RNA polymerase II-specific
- peroxisome proliferator activated receptor binding
- chromatin binding
| Cellular component | - transcription regulator complex
- nucleus
- cytoplasm
- cytosol
- nuclear speck
| Biological process | - cell differentiation
- regulation of transcription, DNA-templated
- cellular response to lithium ion
- negative regulation of chromatin binding
- cellular response to UV
- negative regulation of Wnt signaling pathway
- calcineurin-NFAT signaling cascade
- positive regulation of apoptotic signaling pathway
- negative regulation of transcription by RNA polymerase II
- transcription by RNA polymerase II
- negative regulation of protein binding
- smooth muscle cell differentiation
- transcription, DNA-templated
- regulation of synaptic plasticity
- negative regulation of synapse maturation
- heart development
- negative regulation of dendrite morphogenesis
- intrinsic apoptotic signaling pathway in response to DNA damage
- positive regulation of tumor necrosis factor production
- branching involved in blood vessel morphogenesis
- cellular respiration
- positive regulation of apoptotic process
- inflammatory response
- muscle cell development
- positive regulation of transcription by RNA polymerase II
- negative regulation of pri-miRNA transcription by RNA polymerase II
- cellular response to ionomycin
- cytokine production
- long-term memory
- brain-derived neurotrophic factor receptor signaling pathway
- negative regulation of neuron apoptotic process
- long-term potentiation
- multicellular organism development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | |
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ENSG00000100968 ENSG00000285485 |
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UniProt | | |
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RefSeq (mRNA) | NM_001136022 NM_001198965 NM_001198966 NM_001198967 NM_001288802
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NM_004554 NM_001320043 NM_001363681 NM_001363682 |
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RefSeq (protein) | NP_001129494 NP_001185894 NP_001185895 NP_001185896 NP_001275731
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NP_001306972 NP_004545 NP_001350610 NP_001350611 |
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Location (UCSC) | Chr 14: 24.37 – 24.38 Mb | Chr 14: 56.06 – 56.07 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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