Remeglurant
Chemical compound
- None
- (6-Bromopyrazolo[1,5-a]pyrimidin-2-yl)[(1R)-1-methyl-3,4-dihydro-2(1H)-isoquinolinyl]methanone
- 1309783-00-3
- 24810684
- 32701693
- Y7H8880HMD
- DTXSID501032318
- Interactive image
- C[C@@H]1c2ccccc2CCN1C(=O)c3cc4ncc(cn4n3)Br
InChI
- InChI=1S/C17H15BrN4O/c1-11-14-5-3-2-4-12(14)6-7-21(11)17(23)15-8-16-19-9-13(18)10-22(16)20-15/h2-5,8-11H,6-7H2,1H3/t11-/m1/s1
- Key:TUYZYSNXXSTKQX-LLVKDONJSA-N
Remeglurant (INNTooltip International Nonproprietary Name; developmental code name MRZ-8456) is a drug which acts as a selective antagonist of the mGlu5 receptor.[1][2][3] It is under development by Merz Pharmaceuticals for the treatment of drug-induced dyskinesia but no development has been reported since at least 2016.[3]
See also
- Basimglurant
- Dipraglurant
- Fenobam
- Mavoglurant
- Raseglurant
References
- ^ World Health Organization (2013). "International Nonproprietary Names for Pharmaceutical Substances (INN): Proposed INN: List 109" (PDF). WHO Drug Information. 27 (2). World Health Organization.
- ^ US 7985753, Danysz W, Dekundy A, Hechenberger M, Henrich M, Jatzke C, Nagel J, Parsons CG, Weil T, Fotins J, Gutcaits A, Kalvinsh I, Zemribo R, Kauss V, "Substituted pyrazolo[1,5-A]pyrimidines as metabotropic glutamate receptor modulators.", issued 4 August 2006, assigned to Merz Pharmaceuticals GmbH
- ^ a b "Remeglurant". Adis Insight. Springer Nature Switzerland AG.
- v
- t
- e
mGluR1Tooltip Metabotropic glutamate receptor 1 |
|
---|---|
mGluR5Tooltip Metabotropic glutamate receptor 5 |
|
mGluR2Tooltip Metabotropic glutamate receptor 2 |
|
---|---|
mGluR3Tooltip Metabotropic glutamate receptor 3 |
|
mGluR4Tooltip Metabotropic glutamate receptor 4 |
|
---|---|
mGluR6Tooltip Metabotropic glutamate receptor 6 |
|
mGluR7Tooltip Metabotropic glutamate receptor 7 | |
mGluR8Tooltip Metabotropic glutamate receptor 8 |
|
See also: Receptor/signaling modulators • Ionotropic glutamate receptor modulators • Glutamate metabolism/transport modulators
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e